Guidelines for Nonvariceal Upper Gastrointestinal Bleeding

Endoscopy for Nonvariceal Upper Gastrointestinal Bleeding

Endoscopy for acute nonvariceal upper gastrointestinal bleeding plays an important role in primary diagnosis and management, particularly with respect to identification of high-risk stigmata lesions and to providing endoscopic hemostasis to reduce the risk of rebleeding and mortality. Early endoscopy, defined as endoscopy within the first 24 hours after presentation, improves patient outcome an...

Upper Gastrointestinal Bleeding Score for Differentiating Variceal and Nonvariceal Upper Gastrointestinal Bleeding

Background: Upper gastrointestinal bleeding (UGIB) is a common gastrointestinal emergency. In the place where urgent esophagogastroduodenoscopy (EGD) is unavailable, empirical pharmacological therapy with vasoactive drugs for variceal bleeding or proton pump inhibitors for nonvariceal bleeding is recommended. However, the values of using clinical data for predicting the types of UGIB are unclea...

Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding.

BACKGROUND The management of patients with acute nonvariceal upper gastrointestinal bleeding has evolved substantially over the past 10 years amid a paucity of published consensus guidelines. PURPOSE To provide evidence-based management recommendations that address clinically relevant issues. REVIEW AND CONSENSUS PROCESSES: A multidisciplinary consensus group of 25 voting participants represe...

A 77-year-old man with nonvariceal upper gastrointestinal bleeding.

Comorbidities Affect Risk of Nonvariceal Upper Gastrointestinal Bleeding

BACKGROUND & AIMS The incidence of upper gastrointestinal bleeding (GIB) has not been reduced despite the decreasing incidence of peptic ulcers, strategies to eradicate Helicobacter pylori infection, and prophylaxis against ulceration from nonsteroidal anti-inflammatory drugs. Other factors might therefore be involved in the pathogenesis of GIB. Patients with GIB have increasing nongastrointest...